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Matthias G. Wacker

"The physical and biological realms converge in clinical applications. Our discipline, pharmaceutical science, leverages a deeper understanding of molecular interactions. This is the essence of bioprediction: Creating safer medicines by learning of their complex mechanics."

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Associate Professor Matthias G. Wacker works in the Department of Pharmacy at the National University of Singapore (NUS). After finishing his undergraduate studies in Pharmacy, he earned his doctoral degree in pharmaceutical technology from Goethe University in Frankfurt (Germany), where he also was a principal investigator and completed his habilitation under the guidance of Jennifer Dressman and Jörg Kreuter at the Institute of Pharmaceutical Technology. Before joining NUS, he headed the Department of Pharmaceutical Technology and Nanosciences at the Fraunhofer IME in Frankfurt. He serves on the editorial boards of several prestigious journals (e.g., European Journal of Pharmaceutics and BiopharmaceuticsFrontiers in Chemistry, Journal of Pharmacy and Pharmacology) and has been recognized for his research excellence with awards such as the Eudragit® Best Paper Award (2015) and the Phoenix Pharmaceutics Science Award (2017). He is a member of various committees and organizations, including the United States Pharmacopeial Convention‘s General Chapters – Dosage Forms Expert Committee and the Expert Panel on New Advancements in In-Vitro Product Performance Testing, as well as the International Organization for Standardization’s Technical Committee 229, which is responsible for developing nanotechnology standards.

In his current research, he specializes in employing a quality-by-design approach to create and analyze advanced dosage forms, placing a strong emphasis on biopredictive release and computational techniques to establish in vitro-in vivo correlations. This enables improved formulation designs. Since 2022, he has been acknowledged as one of the World’s Top 2% Scientists by the Standford University Ranking. His work holds immense potential in refining the selection process for optimal formulation prototypes, enabling seamless translation from preclinical to clinical stages.


Associate Professor Matthias G. Wacker, Ph.D.
Department of Pharmacy
National University of Singapore
Wet Science Building (S9) / Level 15

4 Science Drive 2

117544 Singapore

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